Shorten Your Journey
to Parenthood

A Man’s Fertility Can Now be Measured and Ranked

This New Test Has the Power to Predict Pregnancy

Finally, there is a groundbreaking male fertility test that can shorten your journey to parenthood by quantifying a man’s fertility. In a recently completed landmark prospective study, men with a normal score on this new test had more than four times the number of pregnancies than men who scored low. This new test, Cap-Score™, is now a benchmark for measuring male fertility, and the resulting data can be used to predict a man’s probability of generating a pregnancy. A man’s fertility can now, for the first time, be measured and ranked using Cap-Score.

REVOLUTIONARY TECHNOLOGY

Cap-Score evaluates a man’s level of fertility by quantifying the number of sperm cells in the ejaculate capable of generating a pregnancy.  It measures the fundamental biological process that controls fertility and does so by proprietary technology that assesses the sperm’s capacity to fertilize an egg.

The revolutionary Cap-Score technology analyzes sperm on the molecular level. It calculates the percent of sperm cells in the ejaculate capable of fertilizing the egg. Cap-Score is the only test that can predict the man's ability to generate a pregnancy.

Cap-Score detects and analyzes localization patterns using fluorescent microscopy to distinguish fertile from infertile sperm cells, and those capable of going on to generate a pregnancy from those that cannot.


"We now have a tool to properly assess male fertility. We no longer need to rely solely on a semen analysis. The addition of Cap-Score to the clinical evaluation of male fertility offers a functional measure that will help clinicians better counsel couples on how much intervention may or may not be needed,” said Eric Seaman, MD, of New Jersey Urology, a leading practitioner of male reproductive medicine.


PROVIDING INSIGHT FOR MILLIONS OF MEN AND COUPLES

The results from this proprietary male fertility test provide answers for many couples struggling to conceive and become pregnant. Of the millions of men seeking assistance for infertility each year, remarkably, more than 50% are diagnosed as unexplained by current, inadequate methods. Cap-Score’s ability to quantify a man’s probability to generate a pregnancy will help clinicians counsel couples with personalized guidance to shorten their journey to parenthood saving time, emotional distress and money.

Data released by the CDC in 2017, showed for the first time, women aged 30-34 were having more babies than women aged 25-29. The trend is clear that couples are waiting longer to start a family. But that doesn't mean you should wait to get a Cap-Score. Starting early can inform you as to how easy or difficult the path to parenthood will be. Couples will then have time to better manage their journey by starting sooner or seeking advice from a trusted healthcare professional. If the Cap-Score is normal, you will know the man’s fertility should not be an issue and can plan accordingly.

Whether the couple has decided to delay parenthood or the man is diagnosed with male factor infertility, Cap-Score can assist the couple and the clinician in achieving pregnancy.

SHIFTING THE FOCUS TO UNDERSTAND MALE FERTILITY

Cap-Score represents a breakthrough technology that has shifted the focus of understanding a man’s fertility from descriptive measures found with a semen analysis to a functional measure that analyzes the biological process within the sperm cell controlling fertilization. This biological process, known as capacitation, cannot be measured by a semen analysis, but can be quantified by Cap-Score. Data shows that Cap-Score is the best predictor of a man’s fertility.

PUBLISHED STUDY SHOWS PREDICTIVE POWER OF CAP-SCORE

In a recently published prospective study in the journal, Molecular Reproduction and Development, men who exhibited a normal Cap-Score had more than a fourfold increase in generating a pregnancy during the first attempt, compared to those men who scored low. Similarly, men who had a normal score, also had a dramatic and consistently higher ability to generate a pregnancy in both the second and third attempts.*

In this study, Cap-Score and clinical pregnancy outcomes were analyzed for 91 couples. Based on their Cap-Scores, men were separated into groups that categorized them by their probability to generate a pregnancy. The published data showed that men with normal Cap-Scores generated four times the number of pregnancies in the first attempt than men with low Cap-Scores.*

Next, the study tested the ability of the traditional semen analysis to measure a man’s fertility and predict his probability of generating a pregnancy, versus Cap-Score. This was done by comparing the semen analysis measures -- sperm count, motility, volume -- of men who were and were not successful in generating a pregnancy. Of all sperm measures, Cap-Score alone was deemed the most appropriate measure and predictor of a man’s ability to generate a pregnancy. Simply stated, Cap-Score is the only proven measure of a man’s fertility.

In contrast to the predictive power of Cap-Score, traditional semen analysis measures were not related to the man’s ability to generate a pregnancy.

A separate and independently published review demonstrated that the use of Cap-Score as part of the standard of care not only increased clinical pregnancy rates, but also greatly reduced medical costs and enabled a more personalized approach to the treatment of infertility.

The potential increase in clinical pregnancy rates and cost savings attributable to Cap-Score, consistently improve with age. The Cap-Score therefore increases in clinical and economic value for couples who would otherwise have a hard time conceiving.

VALUE OF CAP-SCORE TO ALL COUPLES

The Cap-Score, whether normal or low, allows the clinician along with the couple, to determine what degree of fertility assistance or intervention may be needed. If you are actively trying to conceive or just thinking about starting a family, knowledge of his Cap-Score can highlight where potential issues may lie, be it the man or the woman. Cap-Score can serve as the initial guide to what steps you should take first as a couple and how soon you should take them.

Even with a low Cap-Score, conception is still possible. As with any Cap-Score result, including a normal score, it is always advantageous to speak with a reproductive specialist. Fertility is never a finite measure. It’s dynamic and can be influenced by any number of male or female factors. As such, fertility exists in a low to high spectrum. Depending on the man’s probability to generate a pregnancy, along with any other contributing factors of the couple, a reproductive specialist may suggest different degrees of intervention, or none at all.

Male fertility exists in a low to high continuum, rather than a binary "fertile vs infertile" categorization defined by a specific cut-off.


"The ability to determine the man’s probability of generating a pregnancy is a substantial advance for all couples when planning their families. This is particularly important when childbirth is being delayed resulting in an increased likelihood of encountering potential problems," said Gianpiero Palermo, MD, PhD, Director of Assisted Fertilization and the Andrology Laboratory at the Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine.


Cap-Score is also a powerful tool when it comes to understanding and managing the man’s fertility. Cap-Score can help assess substances that may be beneficial or harmful to a man’s reproductive system. Cap-Score provides a way to track effects on the man’s fertility, and more importantly, identify whether these effects are positive or negative. Everyday medications we take may have a negative impact on fertility. Conversely, there are supplements and suggested lifestyle changes purported to improve a man’s fertility. Cap-Score offers a way to measure the man’s fertility by providing a mechanism to closely track the effects of a suggested regimen or lifestyle change, and whether it increases, decreases or maintains your current level of fertility.

Cap-Score Can Shorten Your Journey to Parenthood

Cap-Score is a new and revolutionary technology you can now use to help guide you on your path to parenthood. It’s like a compass, pointing you in the right direction. Cap-Score helps you to take the most effective path, with the least amount of obstacles, on your journey to parenthood.

*IUI protocol is the best way to study a man’s fertility and link to his probability of pregnancy because it best controls the variables in a study such as this.

Cap-Score™ Test – the Tool to Assess a Man’s Fertility

There is now a male fertility test that can shorten your journey to parenthood. It is the Cap-Score™ test, a new benchmark for measuring male fertility. Previously, there was no measurement of a man’s fertility. But now there is, quantifying the ability of a man to create a pregnancy.

The Cap-Score test makes it possible for you to take control of your personal fertility journey and predict your probability of creating a pregnancy - before you even start.

Whether you’re just thinking about starting a family, actively trying at home, or even if you’ve been struggling to get pregnant, Cap-Score provides incredible insight for any couple.

Know Your Probability of Conception

A man’s probability of creating a pregnancy can range from 7% to 80%. Knowing where the man falls within this range, gives couples the information necessary to make informed decisions about their fertility.

When a Cap-Score test result is above 27.4, there is a greater than fourfold increase in conception during the first attempt, and a threefold increase during the first three attempts.

With a Cap-Score test result in the teens, conception is still possible, but perhaps it’s going to take longer and it might be advantageous to speak with a reproductive specialist.

Cap-Score helps clinicians more accurately identify the role male infertility plays in a couple’s journey. It thereby helps identify where the infertility lies, allowing the clinician to personalize treatment options from the start, and dramatically increase success, reduce costs, and shorten your infertility journey.

Knowing your Cap-Score can offer you peace of mind.

Revolutionary Technology for Male Infertility

Male infertility is a large and growing problem. 50% of male infertility cases are unexplained. Traditional semen analysis cannot test a man’s ability to fertilize.

By predicting the man’s probability of creating a pregnancy and becoming a dad, Cap-Score provides a better understanding of potential problems and shortens your infertility journey. Clinical studies show a 300% improvement for first-try pregnancies.

The Cap-Score test provides an assessment of sperm on a molecular level to determine a man’s fertility and his probability of creating a pregnancy.

Cap-Score also is a powerful tool when it comes to understanding and managing your fertility.  Simple changes to lifestyle, diet and exercise may positively improve a man’s fertility. The Cap-Score test offers a way to measure your progress.

Let Cap-Score help guide you and your clinician on a successful journey to parenthood.

Request your Cap-Score test today and increase your chances of success. Visit 'Get Your Cap-Score Here' or email capscore@androvialife.com.

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