Scientific Data and Presentations

Company announcements:

Press Release: Prospective sudy demonstrates that men who had a normal score on a new fertility test, Cap-Score™, had a fourfold increase in pregnancies during the first attempt compared to men with a low score.
Published Manuscript: Jay Schinfeld, Fady Sharara, Randy Morris, Gianpiero D. Palermo, Zev Rosenwaks, Eric Seaman, Steve Hirshberg, John Cook, Cristina Cardona, G. Charles Ostermeier, Alexander J. Travis. Cap-Score™ prospectively predicts probability of pregnancy. Mol. Reprod Dev. 2018; 1-11.

Press Release: Study shows that altering insemination timing can improve a couple’s ability to conceive, either naturally or through assisted reproduction.
Published Manuscript: G. Charles Ostermeier, Cristina Cardona, Melissa A. Moody, Alana J. Simpson, Romeo Mendoza, Eric Seaman, Alexander J. Travis. Timing of sperm capacitation varies reproducibly among men. Mol. Reprod Dev. 2018; 1-10.

Press Release: Study projects the clinical impact of the Cap-Score™ by improving pregnancy rates and saving couples time and money.
Published Manuscript: Babigumira, J.B., Sharara, F.I. & Garrison, L.P. Projecting the potential impact of the Cap-Score™ on clinical pregnancy, live births, and medical costs in couples with unexplained infertility. J Assist Reprod Genet (2017).

Press Release: Studies validate the clinical utility of the Cap-Score™.
Published Manuscript: Cardona CNeri QVSimpson AJ, et al. Localization patterns of the ganglioside GM1 in human sperm are indicative of male fertility and independent of traditional semen measuresMol Reprod Dev201784:423435.
Published Manuscript: Moody MACardona CSimpson AJSmith TTTravis AJOstermeier GCValidation of a laboratory-developed test of human sperm capacitation. Mol Reprod Dev201784:408-422.

Androvia LifeSciences will have a presence at the following scientific meetings in 2018:

ASRM: American Society of Reproductive Medicine
October 6-10, 2018; Denver, Colorado
Booth # 1124

AUA: American Urological Assocation
May 18-21, 2018; San Francisco, CA
Booth # 6075

SSMR: Society for the Study of Male Reproduction
May 20, 2018; San Francisco, CA

ASA: American Society for Andrology
April 21-24, 2018; Portland, OR
Multiple abstracts accepted for poster presentations

Data presented at past scientific meetings:

ASA: American Society for Andrology
April 21-24, 2018; Portland, OR
Multiple abstracts accepted for poster presentations

ASA: American Society of Andrology
April 22-25, 2017; Miami, FL

  • Abstract #P-136Localization patterns of the ganglioside GM1 identify sperm capable of undergoing capacitation and acrosome exocytosis

ASRM: American Society of Reproductive Medicine
October 15-19, 2016; Salt Lake City, UT

  • Abstract #P-354: Capacitation defects are common in men questioning their fertility and are independent of standard semen analysis parameters
  • Abstract #P-523: Capacitation timing varies among men, but is consistent among ejaculates within individuals

AUA: American Urological Association + SSMR Annual Meeting: Society for the Study of Male Reproduction
May 6-10, 2016; San Diego, CA

  • Abstract #MP70-10: Impacts of common semen handling methods on sperm function

ASA: American Society of Andrology
April 2-5, 2016; New Orleans, LA

  • Abstract #12: Consistent differences among men in capacitation timing could personalize IUI/ART
  • Abstract #138: Normal ejaculates, as defined by WHO, can have abnormal capacitation ability
  • Abstract #140: Sperm from fertile men and those seeking fertility exams differ in their ability to capacitate
  • Abstract #137: Reliability estimates for a test of sperm capacitation, a functional complement to semen analysis

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A New Test for Male Infertility is on the Horizon: The Androvia Cap-Score

Male Fertility Doc, January 27, 2016
Coming soon, a company named Androvia will be releasing a new test that assesses the fertilizing ability of a man’s sperm.  Prior to fertilization, an individual sperm must complete three tasks: “capacitation”, “hyperactivation” and the “acrosome reaction”.  Androvia uses technology that identifies the ability of sperm to undergo capacitation.